Postoperative analgesic effects of various quadratus lumborum block approaches following major gynaecological surgery
Phase 4
Not yet recruiting
- Conditions
- myomcectomy and hystrectomy
- Registration Number
- PACTR202303516170041
- Lead Sponsor
- elshatby hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
American Society of Anesthesiologists physical status of 1 or 2 who will be scheduled for elective gynecological surgery via a Pfannenstiel incision under general anesthesia
Exclusion Criteria
Cognitive dysfunction
Obesity (body mass index 35 kg/m2)
Renal dysfunction (estimated glomerular filtration rate < 50)
Coagulopathy, a drug allergy to NSAIDs, paracetamol or the local anaesthetic,
Gastric ulcer,
Pregnancy
Regular opioid or steroid use.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the analgesic effects of quadratus lumborum blocks in post-gynaecological surgery pain management?
How do different quadratus lumborum block approaches compare to standard-of-care analgesia in major gynaecological surgery outcomes?
Which biomarkers correlate with optimal response to quadratus lumborum block techniques in myomectomy and hysterectomy patients?
What are the potential adverse events associated with various quadratus lumborum block methods post-major gynaecological surgery?
Are there combination analgesic strategies involving quadratus lumborum blocks and systemic opioids for enhanced postoperative pain relief in gynaecological procedures?