Margin reduction in radiotherapy of high grade glioma

Phase 3

Recruiting

• Conditions: High grade glioma.; Malignant neoplasm of brain

• Registration Number: IRCT20210215050367N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 192

Inclusion Criteria

Newly diagnosed glioblastoma multiform patients
Newly diagnosed anaplastic astrocytoma patients
Newly diagnosed oligodendroglioma patients
Confirmed diagnosis based on pathologic evaluation
Karnofsky performance index more than 70%

Exclusion Criteria

Uncontrolled diabetes
Uncontrolled high blood pressure
Impossibility of surgery and tissue sampling

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression free survival. Timepoint: At the beginning of the study and then every 3 months in the first year and every 6 months in the following years. Method of measurement: Physical exam and MRI.

Secondary Outcome Measures

Name	Time	Method
Overall survival. Timepoint: Every 3 month in the first year and every 6 month in subsequent years. Method of measurement: Physical exam and MRI.;Pattern of failure. Timepoint: Every 3 month in the first year and every 6 month in subsequent years. Method of measurement: Physical exam and MRI.