High-flow nasal cannulae use in non-tertiary centres for early respiratory distress in newborn infants: The HUNTER trial.

Not Applicable

Completed

• Conditions: Transient tachypnoea of the newborn (TTN); Respiratory - Other respiratory disorders / diseases; Respiratory distress syndrome (RDS); Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12614001203640
• Lead Sponsor: ewborn Research Centre, The Royal Women's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 750

Inclusion Criteria

1. Gestational age 31 weeks' or above by best obstetric estimate
2. Birth weight >1200 grams
3. Age <24 hours
4. Admitted to the special care nursery of a participating centre
5. Require non-invasive breathing support after admission to the special care nursery, or require supplemental oxygen to maintain peripheral oxygen saturation 91-95% for >1 hour

Exclusion Criteria

1. After admission to the SCN, the infants has already received >4 hours of CPAP
2. Previous endotracheal intubation and positive pressure ventilation, or imediate need for endotracheal intubation as determined by the treating paediatrician
3. Known major congenital abnormality which may impact upon the infant's condition after birth (eg. complex congenital cardiac disease, upper airway obstruction, gastrointestinal malformations)
4. Any infant who is judged by their paediatrician to require transfer to a tertiary hospital for ongoing care

Study & Design

• Study Type: Interventional
• Study Design: Not specified