Success and complications of percutaneous nephrolithotomy (PCNL) under general and spinal anesthesia
- Conditions
- renal stone.Calculus of kidneyN 20.0
- Registration Number
- IRCT201111187457N6
- Lead Sponsor
- rology and nephrology research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
all the patients older than 16 years who present with pelvis and/or calyceal stone and are candidate for PCNL surgery. Exclusion criteria:
1- lack of consent for either of general or spinal anesthesia; 2- complete staghorn stone defined as pelvic stone concomitant with at least three calyces stones' 3- single kidney or single functional kidney ptients; 4- patients with a history of ipsilateral renal surgery; 5- patients with high serum creatinin levels ( higher than 2.5) due to prerenal, renal or postrenal azotemia; 6- congenital anatomic abnormality in the kidney undergoing surgery (malrotation, pelvic kidney, horse-shoe kidney); 7- patients who are suitable only for one type of anesthesia due to medical conditions, body habitus (pinal deformity, dificult-to-intubate larynx), etc; 8- any history of hypersensitivity to remifentanyl, propofol, atracurium, spinal anesthesia material; 9- opioid or alcohol addiction and 10- BMI higher than 30
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Stone clearance. Timepoint: 24 hours after intervention. Method of measurement: Abdominal X-ray.;Transfusion rate. Timepoint: From start of surgery untill discharge. Method of measurement: Number of pack cells transfused.;Opioid requirement. Timepoint: Opioid required during the first 48 hours after procedure. Method of measurement: Infusion pump contolled by patient.;Volume of urinary leakage. Timepoint: During the time of hospitalization. Method of measurement: Amount of urinary leakage through nephrostomy tract.;Visceral injury. Timepoint: During the procedure. Method of measurement: According to the sign and symptoms of patient.;Hemoglobin changes. Timepoint: Before and 6 hours after procedure. Method of measurement: Mg/dL according to the lab data.;Serum creatinin changes. Timepoint: Before and 6 hours after procedure. Method of measurement: Mg/dL accoding to the lab data.
- Secondary Outcome Measures
Name Time Method Fluoroscopy time. Timepoint: At the end of procedure. Method of measurement: Time of exposure to X-ray.;Hospitalization time. Timepoint: From admission to discharge from hospital. Method of measurement: Days of hospitalization according to hospital file.