Does Caralluma fimbriata extract (Slimaluma) combined with Morosil extract reduce the risk factors of metabolic syndrome in overweight and obese adults?

• Conditions: Diet and Nutrition - Obesity; Alternative and Complementary Medicine - Herbal remedies; Metabolic and Endocrine - Metabolic disorders; Metabolic syndrome

• Registration Number: ACTRN12613000272796
• Lead Sponsor: Victoria University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-03-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

Overweight or obese (BMI >25), waist circumference of > 94 cm (male), >80 cm (female), Age: 20-60 years, male or female.

Exclusion Criteria

Cigarette smoker, hypertension, all types of heart, Liver and kidney disease, pregnancy, lactating, Type 1 diabetes and weight loss medication.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood sample analysis of obesity markers including adipocytokines and lipid profile[Pre and post intervention];Appetite test via the visual analogue scales (VAS) method and food intake assessment via 3 day food diaries & food freqency questionnaire.[Pre and post intervention for appetite test and food frequency questionnaire. Fortnightly collection of food diaries during the 16 week period.];Anthropometric measurements including body weight, height, body mass index, waist circumference, hip circumference, waist to hip ratio, percentage body fat, bone mineral mass, lean body mass and girth/ circumference measurments.[Anthropometric measurements including body weight, height, body mass index, waist circumference, hip circumference & waist to hip ratio will be conducted pre and post intervention and fortnightly during the intervention.<br>Percentage body fat, bone mineral mass, lean body mass and girth/ circumference measurments will be conducted pre and post intervention.]

Secondary Outcome Measures

Name	Time	Method
Basal metabolic rate (BMR) will be measured using the metabolic cart (closed circuit spirometry) [Pre and post intervention];Physcial activity assessment via physcial activity questionnaire, physical activity diary, accelerometer.[Pre and post intervention];Blood pressure and heart rate will be measured in a seated position using an automated digital BP monitor [Fortnightly during the 16 week intervention period];Continuous glucose monitoring[Pre and post intervention]