Evaluation of the potential beneficial effects of the administration of Ferula communis extract, containing ferutinin, a natural phytoestrogen, in counteracting postmenopausal dysfunctions, in a cohort of 64 wome

Not Applicable

• Conditions: Menopausal women suffering from post-menopausal discomfort; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN78898299
• Lead Sponsor: IRC-FSH -Magna Graecia University of Catanzaro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-16
• Last Update Posted: 9 September 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

1. Postmenopausal women, with a minimum of 12 months of amenorrhea and a follicle-stimulating hormone level above 30 mIU/mL
2. Sexually active life
3. A stable partner
4. Postmenopausal sexual dysfunction

Exclusion Criteria

Women with hormonal therapy, diabetes, cognitive disorders, hormone-dependent tumors, psychiatric disease, liver diseases (except prior cholecystectomy), renal disease, cardiovascular disease, and those who used drugs that decrease sexual desire

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amelioration of Sexual behavior assessed by Sexual Quotient—female version (SQ-F) and the Female Intervention Efficacy Index (FIEI) questionnaires at time 0 and at 90 days of treatment

Secondary Outcome Measures

Name	Time	Method
Evaluation at time 0 and at 90 days of treatment:<br>1.Onset of menopause signs measured using Sexual Quotient—female version (SQ-F) and the Female Intervention Efficacy Index (FIEI) questionnaires<br>2.Plasma free radicals measured using blood test<br>3.Fat Mass (BMI assessment) measured using height (m) and weight (kg)<br>4.Platelet aggregation measured using platelet samples<br>