The effect of vitamin D supplementation on serum Liver enzymes in patients with Non-Alcoholic Fatty Liver Disease

Vice Chancellor for research of Qazvin University of Medical Sciences0 个研究点目标入组 80 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Inclusion Criteria: Older than 12 years of age; high levels of liver enzymes over the past six months (ALT > 40 U/L); serum vitamin D3 level less than 30 ng/ml; diagnosis to have nonalcoholic fatty liver disease confirmed with sonography results; having non-alcoholic fatty liver disease (NAFLD) and rule out of other hepatic-enzymes rising causes such as viral and autoimmune hepatitis and other chronic liver diseases such as hereditary hemochromatosis, Wilson's disease, an a1- Antitripsin enzyme deficiency; pharmaceutical Hepatitis; consumption of Alcohol.

•Pregnancy or lactation; drug abuse; the use of vitamins (multivitamin, vitamin C and vitamin D) in the last 6 months and during the study; weight loss more than 5% during the 6 months before entering the study; diabetes; use of anti-obesity drugs; hypercalcemia; chronic kidney disease; cardio-pulmonary disease; hyperlipidemia which needs medications and Drugs; malignant history; history of the use of effective drugs on the level of ALT such as Valproic acid, Tamoxifen, HMG-COA reductase inhibitors; chemotherapy compounds; Metformin; Statins; Azathioprine; Acetaminophen; antibiotics such as Sulfanamide and Penicillins; Amiodaron; Methotrexate; Isoniazid; Steroids; herbal Medicines; Ursodeoxycholic acid at 3 months before.

发起方

Vice Chancellor for research of Qazvin University of Medical Sciences