The effect of vitamin D supplementation on serum hepatic enzymes, oxidative stress indicators & inflammatory markers in patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled trial

Ahvaz Jundishapur University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2018年2月22日

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•Inclusion Criteria:
•Diagnosis to have non alcoholic fatty liver disease confirmed with sonography result, ages above 18 and serum alanine transaminase enzyme level higher than normal (> 40 U/L). Diabetic patients will include who have been recently diagnosed with diabetes and not using blood glucose lowering drugs or if they consume insulin and metformin, it would pass at least 6 months from starting the treatment and during this period the dose of metformin and insulin are not changed.
•Exclusion criteria:
•Alcohol consumption greater than 20 g per day, pregnancy, lactation, diseases such as hereditary hemochromatosis, Wilson's disease, an enzyme deficiency a1 Antitripsin, history of jejunoileal bypass surgery orgastroplasty, experience to perform the total parenteral nutrition at 6 months before, consomption of hepatotoxic drugs such as calcium channel blocker, high doses of synthetic estrogens, methotrexate, amiodarone, chloroquine, a history of hypothyroidism and Cushing's syndrome. Serum calcium greater than 10.6mg / dl , a history of kidney stones, renal failure, intake of vitamin D,vitamin E and calcium supplements during last 6 months.

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