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The Effect of Ketamine on Control of Aggressive Patients

Phase 3
Conditions
Agitated Patients.
Violent behavior
Registration Number
IRCT20180129038549N5
Lead Sponsor
Esfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
90
Inclusion Criteria

All the patients who intended to damage themselves or others
Altered mental status score (AMSS) +2 or +3
Required physical restraint and parenteral sedation

Exclusion Criteria

serious physical illness
History of heart disease
pregnancy
drug dependence
treatment with a benzodiazepine or neuroleptic within the previous 24 hours
Ketamine and Haloperidol contraindications

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Aggression control. Timepoint: Every 5 minutes. Method of measurement: altered mental status score.
Secondary Outcome Measures
NameTimeMethod
Side effects. Timepoint: Every 15 minutes. Method of measurement: Physical exam.;Frequency of repeat dosing. Timepoint: After 6 hour. Method of measurement: Physical exam.;Vital signs. Timepoint: Every 5 minutes. Method of measurement: Physical exam.;Satisfaction. Timepoint: After 6 hour. Method of measurement: Questionnaire.;Intubation. Timepoint: After 6 hour. Method of measurement: Counts.
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