Comparison between clonidine and Dexmedetomidine as premedication on hemodynamic changes and intraoperative bleeding

Not Applicable

• Conditions: Complications of procedures, not elsewhere classified; Condition 1: Bleeding. Condition 2: Hemodynamic Changes.; Tachycardia (unspecified), Bradycardia (unspecified), Palpitations; R00.0, R00

• Registration Number: IRCT2016011225982N1
• Lead Sponsor: Ahvaz Jundishapur University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Inclusion criteria were as follows: age range of 20 to 50 years, ASA class 1 or 2 and spine surgery candidates. Exclusion criteria included patients with hypertension, diabetes, clotting problems, ischemic heart disease, drug or alcohol abuse, pregnancy, taking beta blockers or calcium channels blockers drugs and operating time of over 120 minutes.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraoperative bleeding. Timepoint: Ending surgery. Method of measurement: Including suction bottle and blood gauzes.

Secondary Outcome Measures

Name	Time	Method
Heart Rate. Timepoint: One minute after intubation, 10, 20, 30 minutes after induction of anesthesia and after extubation. Method of measurement: ECG Monitoring.;Blood Pressure. Timepoint: One minute after intubation, 10, 20, 30 minutes after induction of anesthesia and after extubation. Method of measurement: Invasive blood pressure monitoring.;Mean Arterial Pressure. Timepoint: One minute after intubation, 10, 20, 30 minutes after induction of anesthesia and after extubation. Method of measurement: Invasive blood pressure monitoring.