Text Message Intervention to Improve Adherence in Adolescents and Young Adults With Celiac Disease
- Conditions
- Celiac Disease
- Interventions
- Behavioral: Educational Text Message Reminders
- Registration Number
- NCT02458898
- Lead Sponsor
- Stanford University
- Brief Summary
This is a prospective randomized controlled trial investigating the impact of educational bidirectional text message reminders on gluten free diet adherence among adolescents and young adults with celiac disease age 12-24. Participants will complete a series of online questionnaires assessing quality of life, patient activation, celiac symptoms, and self reported dietary adherence at the beginning and end of the study. Participants will also have their blood drawn to measure Tissue Transglutaminase IgA (TTG IgA) antibody and Deamidated Gliadin Peptide IgA (DGP IgA) at the beginning and end of the study. Lab draws can be done locally, and are at no cost to the participant. Patients are randomized to the intervention or control group based on enrollment TTG IgA. Intervention group receives 45 unique text messages over the 3 month study. A gift card is provided for participation in the study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 61
- Age 12-24
- Celiac disease diagnosed by a gastroenterologist at least 1 year prior to enrollment
- Participant with ability to read email and text messages in English
- Access to a mobile phone
- Unlimited text messaging plan or agreement to receive 45 text messages for the study
- Participant inability to answer survey questions and text prompts in English
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Text Message Intervention Educational Text Message Reminders A series of 45 unique educational text messages sent over a period of 3 months in the evenings. Text messages include humorous reminders, links to online celiac disease resources, and bidirectional questions.
- Primary Outcome Measures
Name Time Method Tissue Transglutaminase IgA (TTG IgA) 3 months Percent change in TTG IgA for each participant pre and post study period
- Secondary Outcome Measures
Name Time Method Patient-reported celiac disease symptom measure (CDI) score 3 months Change in patient-reported celiac disease symptom measure (CDI) questionnaire score pre and post study period
Patient-reported dietary adherence (CDAT) score 3 months Change in patient-reported dietary adherence (CDAT) questionnaire score pre and post study period
Deamidated Gliadin Peptide IgA (DGP IgA) 3 months Percent change in DGP IgA for each participant pre and post study period
Patient Activation Measure (PAM) score 3 months Change in Patient Activation Measure (PAM) questionnaire score pre and post study period
NIH-PROMIS quality of life score 3 months Change in NIH-PROMIS quality of life questionnaire score pre and post study period
Trial Locations
- Locations (1)
Stanford University Pediatric Gastroenterology Department
🇺🇸Palo Alto, California, United States