on-antibiotic versus Antibiotic Prophylaxis for Recurrent Urinary Tract Infections

Completed

• Conditions: rinary tract infections; Urological and Genital Diseases; Other disorders of urinary system

• Registration Number: ISRCTN50717094
• Lead Sponsor: Academic Medical Centre (AMC) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-12
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 560

Inclusion Criteria

1. Women aged 18 years or older
2. At least three symptomatic urinary tract infections (UTIs), uncomplicated or complicated, in the year preceding study inclusion OR already using any form of prophylaxis to prevent recurrences of urinary tract infections and at least three symptomatic urinary tract infections in the year befort the start of the prophylaxis

Exclusion Criteria

1. Life expectancy less than or equal to one year
2. Legally incapable
3. A renal transplant in the medical history
4. Contraindications for or relevant interactions with trimethoprim-sulfamethoxazole (TMP/SMX)
5. Additional exclusion criteria for trial A (pre-menopausal women randomised to either cranberry capsules or TMP/SMX):
5.1. Breastfeeding, pregnancy, or pregnancy wish for the next year
5.2. Contraindications for or relevant interactions with cranberries

Study & Design

• Study Type: Interventional
• Study Design: Not specified