Comparison of Continuous Femoral Nerve Block (CFNB/SA) and Continuous Femoral Nerve Block with Mini-dose Spinal Morphine (CFNB/SAMO) for Postoperative Analgesia after Total Knee Arthroplasty (TKA)

Phase 2

Completed

• Conditions: Total Knee Arthroplasty; Spinal Anesthesia; Mini- dose Spinal Morphine

• Registration Number: TCTR20150609003
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2013-05-15
• Study Start: 2015-06-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

ASA I-III patients scheduled for elective unilateral TKA under spinal anesthesia (SA)

Exclusion Criteria

- age < 40 years or > 80 years
- body mass index (BMI) > 45
- renal insufficiency (Cr > 1.5 mg/dl)
- pre-existing neurological deficit
- inability to comprehend pain scales
- chronic opioid use
- contraindications to either neuraxial block or FNB

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS pain score Post operative 1, 6, 12, 24, 36 and 48 hours Interview

Secondary Outcome Measures

Name	Time	Method
Tramadol IV requirement Post operative 1, 6, 12, 24, 36 and 48 hours Measurement,Postoperative nausea and vomiting During postoperative from 1-6,6-12 and 12-24 hours Number of patients with outcome