Comparison of bedside methods to estimate CVP
- Conditions
- Heart disease, shock
- Registration Number
- NL-OMON22937
- Lead Sponsor
- A.J. Fogteloo, MD, PhD Head of the Subdepartment of Acute Medicine, Leiden University Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 78
Inclusion Criteria
= 18 years old - admitted to ward or the intensive care unit
- Indwelling central venous catheter in left jugular vein or left subclavian vein OR indwelling peripherally inserted central catheter.
- Both capacitated as incapacitated adults are included
Exclusion Criteria
Inability to assess CVP by both methods due to cervical adiposity, lack of echogenic window, etc.
- Pregnancy
- Undergoing positive pressure ventilation
- Severe tricuspid regurgitation
- Superior vena cava syndrome
- Neurotrauma
- Any condition that in the opinion of the investigator would interfere with the measurements.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in test characteristics (sensitivity and specificity after determination of optimal cut-off with receiver operating characteristic curves as compared to the gold standard of the CVP measured in the superior vena cava by means of a central venous catheter) of the bedside tests to assess elevated CVP (according to Lewis and Borst, with and without correction for the vertical distance between the right atrium and the sternal angle; ultrasonographic measurement of maximum width and collapsibility of the IVC; and ultrasonographic measurement of the diameter and height of the IJV).<br>
- Secondary Outcome Measures
Name Time Method - The correlation between estimates of CVP as measured according to Lewis and Borst (with and without correction for the vertical distance between the right atrium and the sternal angle), ultrasonography of the IVC and ultrasonography of the IJV.<br>- The correlation of the above-mentioned measures with the gold standard; the CVP measured in the superior vena cava by means of a central venous catheter.