Comparison of non-invasive bedside methods to estimate central venous pressure

Completed

Conditions: centraal veneuze druk
druk in de centrale aders
10019280
10011954

Registration Number: NL-OMON52477

Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 78

Inclusion Criteria

- >= 18 years old
- Admitted to the ward or intensive care unit
- Indwelling central venous catheter in jugular vein or subclavian vein OR
indwelling peripherally inserted central catheter

Exclusion Criteria

- Inability to assess CVP by both methods due to cervical adiposity, lack of
echogenic window, etc.
- Pregnancy
- Undergoing positive pressure ventilation
- Severe tricuspid regurgitation
- Superior vena cava syndrome
- Neurotrauma
- Any condition that in the opinion of the investigator would interfere with
the measurements.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences in test characteristics (sensitivity and specificity after<br /><br>determination of optimal cut-off with receiver operating characteristic curves<br /><br>as compared to the gold standard of the CVP measured in the superior vena cava<br /><br>by means of a central venous catheter) of the bedside tests to assess elevated<br /><br>CVP (according to Lewis and Borst, with and without correction for the vertical<br /><br>distance between the right atrium and the sternal angle; ultrasonographic<br /><br>measurement of maximum width and collapsibility of the IVC; and<br /><br>ultrasonographic measurement of the diameter and height of the IJV).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- The correlation between estimates of CVP as measured according to Lewis and<br /><br>Borst (with and without correction for the vertical distance between the right<br /><br>atrium and the sternal angle), ultrasonography of the IVC and ultrasonography<br /><br>of the IJV.<br /><br>- The correlation of the above-mentioned measures with the gold standard; the<br /><br>CVP measured in the superior vena cava by means of a central venous catheter.</p><br>