Impact of Lifestyle Modification on Prevention of Dementia, Chronic Kidney Disease, Diabetes, Chronic Obstructive Pulmonary Disease, Cancers and Cardiovascular Disease in a Thai General Population: Cluster Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 3,600
- 试验地点
- 2
- 主要终点
- Dementia
研究概览
简要总结
This is a community-based cluster randomized control trial aimed to investigate the impact of lifestyle modification (diet, physical activity, alcohol drinking and smoking) on the development of dementia, diabetes, chronic kidney disease, cancers, chronic obstructive pulmonary disease and cardiovascular disease in an intermediate risk population in mixed urban-rural areas of Ubon Ratchathani.
详细描述
This is a community-based cluster randomized control trial aimed to investigate the impact of lifestyle modification (diet, physical activity, alcohol drinking and smoking) on the development of dementia, diabetes, chronic kidney disease, cancers, chronic obstructive pulmonary disease and cardiovascular disease in an intermediate risk population in mixed urban-rural areas of Ubon Ratchathani.
Objectives:
- examine the impact of lifestyle modification on the development of dementia, diabetes, chronic kidney disease, cancers, chronic obstructive pulmonary disease and cardiovascular disease in an intermediate risk population in Ubon Ratchathani
- examine the economic impact of lifestyle modification on prevention of dementia, diabetes, chronic kidney disease, cancers, chronic obstructive pulmonary disease and cardiovascular disease in an intermediate risk population in Ubon Ratchathani
Study design: community-based cluster randomized control trial
Setting: 60 villages randomly selected from mixed urban-rural areas in 15 districts of Ubon Ratchathani province.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Thai nationality
- •Age 45-75 years
- •Have resided in the Ubon Ratchathani's villages for at least 1 year
- •Those giving written informed consent to participate in the research project
排除标准
- •Known case of dementia, chronic kidney disease, diabetes, chronic obstructive pulmonary disease, cancers and cardiovascular disease
- •Unable to communicate well in Thai
- •Unable to move or get physical exercise
- •Those at risk of having complications from performing physical exercise
- •Those diagnosed with cancers of any system/ organ or those in the end of life period
结局指标
主要结局
Dementia
时间窗: 10 years
Number of participants with dementia. Incident dementia will be diagnosed by medical specialists (Neuro-Med) following a battery of screening tests, including mini-mental state exam, depression and clock drawing tests.
次要结局
- Mortality(5 and 10 years)
- Blood sugar(1, 2, 5 and 10 years)
- Cardiovascular disease(5 and 10 years)
- Cancers(5 and 10 years)
- Type 2 diabetes mellitus(3, 5 and 10 years)
- Chronic obstructive pulmonary disease(5 and 10 years)
- Blood lipids(1, 2, 5 and 10 years)
研究者
P Chamnan
Principal Investigator
Sanpasitthiprasong Hospital