ovel treatment of Acanthamoeba Keratitis
Not Applicable
- Conditions
- Health Condition 1: H160- Corneal ulcer
- Registration Number
- CTRI/2019/08/020875
- Lead Sponsor
- V Prasad Eye Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other (Terminated)
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age equal to or more than 18 years.
2) Male or female
3) Stromal infiltrate size between <6 mm and involving anterior to mid stroma only.
4) Corneal scraping positive for Acanthamoeba cysts in direct smear examination by any one or more of the methods used.
Exclusion Criteria
1) The corneal scrapings are negative for Acanthamoeba.
2)The patient has a history of allergy to Miltefosine
3) The cornea or sclera has been perforated or perforation is impending.
4)The unaffected eye is legally blind. .
5)The patient is known to be HIV positive or diabetic.
6)The initial culture shows significant growth of bacteria ( >10 colonies) or fungus.
7)Both eyes are infected.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Size of the infiltrate and inflammatory signsTimepoint: Size of the infiltrate and inflammatory signs. <br/ ><br>complete Resolution of infection or resolving infection
- Secondary Outcome Measures
Name Time Method umber of patients went to therapeutic TreatmentTimepoint: 1 month