Effect, safety and action of Ketotifen associated with Famotidine in the treatment of facial stains.

Not Applicable

• Conditions: Skin disorders; C16.131.831

• Registration Number: RBR-7g4gp4
• Lead Sponsor: Faculdade de Medicina de Botucatu (FMB - Unesp)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

women; aged 18 to 60 years; moderate to severe facial melasma; no treatment for at least 30 days.

Exclusion Criteria

dermatoses with photosensitivity; history of hypersensitivity to ketotifen or famotidine; personal history of liver disease; pregnant women; lactating women.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected outcome 1: reduction of facial melasma pigmentation, verified by variation of the mMASI, in the before and after intervention measurements based on the images photographed in the two moments.

Secondary Outcome Measures

Name	Time	Method
Expected outcome 2: reduction of facial melasma pigmentation, verified by colorimetric index variation.