Cognitive Processing Therapy vs. Sertraline for the Treatment of PTSD & SUD in Egyptian Patients

Phase 1

Completed

• Conditions: Psychologic Manipulation
• Interventions: Other: Placebo Control; Behavioral: Cognitive processing therapy; Drug: Sertraline

• Registration Number: NCT03469128
• Lead Sponsor: British University In Egypt

Brief Summary

The present research was aimed at comparing the effects of Cognitive Processing Therapy (CPT) with the effects of Sertraline in treating patients who have dual diagnosis PTSD \& SUD. The present study examines the extent to which CPT is effective in treating PTSD symptoms for patients with PTSD and SUD.

Detailed Description

Patients with co-occurrence PTSD \& SUD disorders were grouped into 3 groups: first: Cognitive Processing Therapy (CPT) in which participants completed 12 sessions of CPT. Second: were treated by Sertraline. Third: a placebo control group.

Study Timeline

• Study Start: 2016-01-01
• Study First Submitted: 2018-01-31
• Study First Submitted QC: 2018-03-12
• Study First Posted: 2018-03-19
• Primary Completion: 2020-01-01
• Study Completion: 2020-01-01
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-30
• Last Update Posted: 2021-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Patients diagnosed with SUD

Exclusion Criteria

• Patients diagnosed with other psychotic disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	Placebo Control	Placebo Control group
Cognitive processing therapy	Cognitive processing therapy	Cognitive Processing Therapy (CPT) in which participants completed 12 sessions of CPT
Sertraline	Sertraline	Patients with co-occurrence PTSD \& SUD disorders were treated by Sertraline.

Primary Outcome Measures

Name	Time	Method
Questionnaire	3 Months	A psychological parameter will be measured to check the efficacy of CPT against medication for the treatment for co-current PTSD \& SUD. The groups will be examined to show if any significant reductions in PTSD and SUD symptoms was obtained over time.