Study to see if blood level of myoglobin or creatinine phosphokinase predict kidney failure in patients admitted with muscle damage after injury.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Post traumatic rhabdomyolysis
- Registration Number
- CTRI/2012/08/002892
- Lead Sponsor
- Christian Medical College Fluid Research Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
Inclusion Criteria
All patients admitted with post-traumatic rhabdomyolysis with creatine phosphokinase of >5000 IU/litre
Exclusion Criteria
Age <18 or >80 years
Non traumatic rhabdomyolysis
Chronic renal failure
No consent or assent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Renal Failure {An abrupt (within 48 hours) reduction in kidney function currently defined as an absolute increase in serum creatinine of more than or equal to 0.3 mg/dl (� 26.4 μmol/l), a percentage increase in serum creatinine of more than or equal to 50% (1.5-fold from baseline), or a reduction in urine output (documented oliguria of less than 0.5 ml/kg per hour for more than six hours}Timepoint: ICU stay
- Secondary Outcome Measures
Name Time Method 1. Need for dialysis <br/ ><br>2. Number of ventilator free days <br/ ><br>3. Number of ICU days <br/ ><br>4.ICU mortality <br/ ><br>5. In Hospital MortalityTimepoint: 1. ICU stay <br/ ><br>2. ICU <br/ ><br>3. ICU <br/ ><br>4. ICU <br/ ><br>5. Hospital