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Clinical Trials/NCT04289181
NCT04289181
Completed
Not Applicable

A Pilot Trial Assessing the Feasibility of Providing Medically-tailored Meals to Patients Diagnosed With Heart Failure

Thomas Jefferson University1 site in 1 country30 target enrollmentMarch 5, 2020
ConditionsHeart Failure

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Failure
Sponsor
Thomas Jefferson University
Enrollment
30
Locations
1
Primary Endpoint
Feasibility: Retention
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The goal is to conduct a pilot trial that provides 4 weeks of medically-tailored meals (MTM) to patients with heart failure (HF) via collaboration with the Philadelphia Meals on Wheels chapter to assess the feasibility of such an intervention. Patients will be enrolled during either an inpatient hospitalization or an emergency department (ED) visit, and will be randomized into 1 of 2 arms: 1) MTM or 2) usual care that follows guideline-directed medical therapy (GDMT). Evidence gathered from this study will guide the design of a larger randomized controlled trial to be submitted to the National Institutes of Health (NIH) to evaluate the scalability, sustainability and cost-effectiveness of MTM for improving outcomes for patients with HF.

Detailed Description

While medication adherence and transitions from hospitalization to home care play important roles in heart failure (HF) care, the majority of HF maintenance is by the patients in the home. Despite the availability of evidence-based guidance and treatments, many patients with HF do not achieve optimal outcomes. In prior work, patients with HF identified primary needs of improved access to food and nutrition education. Dietary recommendations for HF in clinical practice have historically emphasized the reduction of a single micronutrient (sodium) and fluid management, which oversimplifies the complexity between multiple dietary inadequacies, including micronutrient deficiencies, and HF pathophysiology. In addition, patients may have other comorbidities thus requiring further modification of the patient's diet. As a result, several innovative models for food services have emerged to address patient needs for improved healthy food access. Currently, select non-profit organizations across the U.S. deliver millions of medically-tailored meals (MTM) to patients with chronic illnesses, based on the premise that food can be as helpful as medicine in improving patient outcomes. Small studies assessing MTM in isolation have demonstrated reduced healthcare utilization and cost, however, no randomized trials have assessed the sustained impact of this intervention. The goal is to evaluate the feasibility of providing medically-tailored meals to patients with HF. Data from this study can be used to design further studies testing the effectiveness of MTM on improving outcomes for patients with HF. Meals on Wheels, a provider of meals to senior citizens across the country, has only recently begun piloting medically-tailored meals, and this presents the opportunity to work with the organization to test the feasibility of MTM in the Philadelphia region.

Registry
clinicaltrials.gov
Start Date
March 5, 2020
End Date
April 1, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

AnnaMarie Chang

Associate Professor, Director of Clinical Research Operations

Thomas Jefferson University

Eligibility Criteria

Inclusion Criteria

  • Have a diagnosis of acute heart failure (AHF), as determined by the treating physician
  • Are 50 years of age or older
  • Are a patient in the ED or inpatient at TJUH or Methodist Hospita
  • Are able to keep food fresh for a week after delivery (e.g., not homeless)
  • Have an address that is within the delivery radius of Meals on Wheels-Philadelphia
  • Be able and willing to be available for follow-up contact

Exclusion Criteria

  • Pregnant, planning to be pregnant, or currently breastfeeding.
  • Does not eat by mouth (i.e. receives tube feeds or total parenteral nutrition \[TPN\])
  • Psychiatric co-morbidity that would preclude study participation
  • Non-English speaking
  • In police custody or incarcerated
  • Currently receiving MTM from Meals on Wheels or another provider

Outcomes

Primary Outcomes

Feasibility: Retention

Time Frame: 12 weeks

Feasibility will be measured by the percent of enrolled patients who complete follow-up visits at 12 weeks

Feasibility: Enrollment

Time Frame: One year

Feasibility will be measured by the number of patients enrolled in the study. We aim to enroll 30 total patients.

Secondary Outcomes

  • Feasibility of administering the Dutch Heart Failure Knowledge Scale(Baseline, 4 weeks, 12 weeks)
  • Patient satisfaction with intervention(4 weeks)
  • Feasibility of administering the patient activation measure short form (PAM-13)(Baseline, 4 weeks, 12 weeks)
  • Feasibility of administering the Kansas City Cardiomyopathy Questionnaire 12 (KCCQ-12)(Baseline, 4 weeks, 12 weeks)
  • Feasibility of administering the Minnesota Living with Heart Failure Questionnaire (MLHF)(Baseline, 4 weeks, 12 weeks)

Study Sites (1)

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