Comparison of the Antibacterial Effects of 0.2% Chlorhexidine, Matrica, and Normal Saline Mouthwashes in Hospitalized Patients in IC
Not Applicable
- Conditions
- ventilator associated pneumonia.Pneumonia due to staphylococcus, Pneumonia due to Escherichia coli, Pneumonia due to Streptococcus pneumoniae, Pneumonia due to PseudomonasJ15.1, J15
- Registration Number
- IRCT201204287821N1
- Lead Sponsor
- Research Deputy of Golestan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Hospitalization in ICU; Age= 15 years old; Intubation and mechanical ventilation for 48 hours; having NG tube for 48 hour; Not having any of the following conditions: Respiratory and systemic infection, History of antibiotic therapy before admission, Autoimmune diseases and malignancies, History of allergy to mouthwash, History of radiation therapy and immunosuppressive therapy including corticosteroid, Use of any kind of antimicrobial mouthwash within two months before admission.
Exclusion Criteria
Re-intubation; Occurrence of any reaction to Mouthwashes; Patient death or transfer to another unit; Pulmonary infection.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Staphylococus aureus, Pneumoccocus, Enterococcus, Pseudomonas, and Escherichia coli number of celles in colony. Timepoint: First sample at the time of admission to the ward before mouth washing and the next sample 48 hours after intervention. Method of measurement: CFU (Colony-Forming Unit).
- Secondary Outcome Measures
Name Time Method Any reaction to Mouthwashes. Timepoint: after using of mouthwashes. Method of measurement: inspection.