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临床试验/NCT04449302
NCT04449302已完成不适用

Clinical Evaluation of Papilla Index Around Immediate Implant Placement in Mandibular Molars Using Chairside Customized Healing Abutment Versus Submerged Healing :A Randomized Controlled Clinical Trial

Cairo University1 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2021年3月25日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
22
试验地点
1
主要终点
Papilla Index

研究概览

简要总结

The original implant treatment protocol recommended that the implant should be placed in a fully healed site and covered with mucosa after placement to ensure osseointegration. The reason was to protect the implant site from bacterial contamination and to avoid loading of the implant. After that, a second stage surgical procedure had to be performed to expose the implant to connect the abutment. However, it was shown that a one stage or non-submerged (NS) approach can lead to successful and predictable outcomes.

Customized healing abutments can be used in the non-submerged protocol, protecting and containing the bone substitute during healing, preserving the alveolar contour, preventing food impaction, and eliminating the need for a second stage surgery and. By means of this technique, critical and subcritical contours can be projected speeding up the peri-implant soft tissue conditioning phase in order to achieve final natural-like restorations.

This randomized controlled trial will compare the clinical and radiographic hard and soft tissue changes using chairside customized healing abutment versus submerged healing following immediate implant placement in mandibular molars through measuring the horizontal ridge changes by CBCT , the crestal bone loss by a standardized digital x-ray and the soft tissue changes by the pink esthetic score (PES).

详细描述

Immediate implant placement in extraction sockets was used to (i) reduce the number of surgical procedures (ii) preserve the dimensions of the alveolar ridge and (iii) reduce the interval between the removal of the tooth and the insertion of the implant supported restoration.

Flapless extraction is a technique aimed towards leaving the periosteum undisturbed by extracting the tooth with minimal trauma using periotomes without flap reflection. They also found less crestal bone loss around immediate implants placed in flapless extraction sockets in compared to implants placed by elevating a flap, due to greater blood supply and less postoperative swelling and pain.

Submerged healing and absence of loading was proposed during the early stage of osseointegration. Such a two-stage approach, based on a period of submerged healing aimed at optimizing the process of new bone formation and remodeling that follows implant placement is considered the gold standard procedure. It requires a second surgery to connect the abutment. This second surgical procedure is generally a minor one; thus, it is not particularly uncomfortable for the patient and offers the possibility to perform soft tissue management procedures around healed implants which may result in a better long-term prognosis. On the other hand, the desire to provide faster and less invasive treatment to patients, as well as to avoid postponing implant load and prosthesis delivery, has led to one-stage surgery (non-submerged healing). In this approach the implant and the healing abutment are placed in a single procedure so it remains exposed in the oral cavity during the osseointegration period.

The provisional restoration or a custom abutment can act as a "prosthetic socket-sealing" to protect, contain and maintain the blood clot and bone-graft material during the healing phase of treatment.

The aim of this randomized clinical trial is to evaluate the clinical and radiographic hard and soft tissue changes using chairside customized healing abutment versus submerged healing following immediate implant placement in mandibular molars.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

盲法说明

single blinded

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Patients age between 20 and 70 years old.
  • •Patients with non-restorable mandibular molars
  • •Medically free.
  • •Integrity of the extraction socket wall
  • •Patients who are able to sign an informed consent form.
  • •Cooperative, motivated and hygiene conscious Patients.
  • •Patients who are able to come for the follow up appointments.

排除标准

  • •Patients with compromised general health conditions that would impair bone healing including: Past or present history of bone irradiation Patients taking bisphosphonates
  • •Teeth with acute periapical pathosis
  • •Heavy Smokers
  • •Parafunctional habits
  • •Pregnant females
  • •Drug abusers
  • •Uncontrolled diabetes

研究组 & 干预措施

Immediate molar implant with customized healing abutment

Experimental

Patients will receive an immediate mandibular molar implant with customized healing abutment

干预措施: Immediate molar implant with customized healing abutment (Procedure)

Immediate molar implant with submerged healing

Active Comparator

Patients will receive an immediate mandibular molar implant with submerged healing

干预措施: Immediate molar implant with customized healing abutment (Procedure)

结局指标

主要结局

Papilla Index

时间窗: 1 year follow up

JEMT Index (mm.)

次要结局

  • Satisfaction index(1 year follow up)
  • Hard tissue horizontal ridge changes (bucco lingual)(1 year follow up)
  • Crestal bone loss(1 year follow up)
  • Soft tissue profile(1 year follow up)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Nabil Ibrahem

Teaching assistant

Cairo University

研究点 (1)

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