Comparative study on dyspeptic symptom generation and gastroduodenal capsaicin/TRPV1 expression between Korea and Japa

Not Applicable

Completed

• Conditions: Functional dyspepsia

• Registration Number: JPRN-UMIN000009673
• Lead Sponsor: Keio University

Brief Summary

pper gastrointestinal symptoms are more common in subjects with a higher consumption of spicy foods, younger age and female gender, regardless of TRPV1 genotypes and the H. pylori infection status.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients who have structural disease including erosive gastritis and GERD. 2. Patients who have history of upper GI operation 3. Patients whose causes of dyspepsia are obvious like taking much food, drink, NSAIDs, much stress, and so on. 4. Patients who have history of brain structual disease, schizophrenia, and depression. 5. Alcohol or drug dependent patients. 6. Patients who have severe disorder of endocrine system like hyperthyroidism. 7. Patients who have severe disorder of cardiovascular system, liver system, renal function, infection, and hematopoietic organ. 8. Patients who have allergic reaction for some drugs for gastrointestinal system. 9. Pregnancy or lactation woman. Patients who hope pregnancy during study. 10. Patients who took H. pylori eradication therapy within 6 months 11. Patients who are difficult to stop taking drugs like gastrointestinal drugs, anti-choline drugs, anti-depressant, and so on. 12. Suspitious for IBS 13. Any other patients which primary doctor judges them appropriate for this study.

Study & Design

• Study Type: Observational
• Study Design: Not specified