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临床试验/JPRN-UMIN000009673
JPRN-UMIN000009673已完成未知

Comparative study on dyspeptic symptom generation and gastroduodenal capsaicin/TRPV1 expression between Korea and Japan - Comparative study on dyspeptic symptom generation and gastroduodenal capsaicin/TRPV1

Keio University0 个研究点目标入组 200 人开始时间: 2012年12月31日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
入组人数
200

研究概览

简要总结

pper gastrointestinal symptoms are more common in subjects with a higher consumption of spicy foods, younger age and female gender, regardless of TRPV1 genotypes and the H. pylori infection status.

研究设计

研究类型
Observational

入排标准

年龄范围
20years-old 至 ot applicable(—)
性别
All

入选标准

  • 未提供

排除标准

  • 1. Patients who have structural disease including erosive gastritis and GERD. 2. Patients who have history of upper GI operation 3. Patients whose causes of dyspepsia are obvious like taking much food, drink, NSAIDs, much stress, and so on. 4. Patients who have history of brain structual disease, schizophrenia, and depression. 5. Alcohol or drug dependent patients. 6. Patients who have severe disorder of endocrine system like hyperthyroidism. 7. Patients who have severe disorder of cardiovascular system, liver system, renal function, infection, and hematopoietic organ. 8. Patients who have allergic reaction for some drugs for gastrointestinal system. 9. Pregnancy or lactation woman. Patients who hope pregnancy during study. 10. Patients who took H. pylori eradication therapy within 6 months 11. Patients who are difficult to stop taking drugs like gastrointestinal drugs, anti-choline drugs, anti-depressant, and so on. 12. Suspitious for IBS 13. Any other patients which primary doctor judges them appropriate for this study.

研究者

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