Evaluation of the effectiveness of two- and four-drugs regimens in eradication of H pylori
Phase 3
Recruiting
- Conditions
- Peptic ulcer disease and H pylori infection.Helicobacter pylori [H.pylori] as the cause of diseases classified to other chaptersB98.0
- Registration Number
- IRCT20131124015510N5
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
People with peptic ulcer or gastro-duodenal erosion
Helicobacter pylori infection on a pathological biopsy or Rapid urease test
who have not previously received a Helicobacter pylori eradication regimen
Exclusion Criteria
Age under 18 years
Pregnancy and lactation
Concomitant use of anticoagulants, corticosteroids or ketoconazole
atients who have a history of gastric surgery
Patients with a confirmed history of severe heart or lung failure, chronic kidney failure, chronic liver disease or a history of cancer.
History of drug allergy to the drugs of this study
Previous history of Helicobacter pylori eradication
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori infection rat. Timepoint: Evaluation of Helicobacter pylori infection at the beginning of the study and then 8 weeks after receiving the desired treatment regimen. Method of measurement: Measurement of Helicobacter pylori infection variable by pathology at the beginning of the study and confirmation of eradication at the end of the study by fecal antigen method.
- Secondary Outcome Measures
Name Time Method H pylori infection eradication. Timepoint: initiation of study and 8 weeks after end of treatment. Method of measurement: At the beginning of treatment by pathology and at the end of treatment by fecal antigen of Helicobacter pylori.