The Efficacy of REHACOP Program in Schizophrenia

Not Applicable

Completed

• Conditions: Schizophrenia
• Interventions: Behavioral: Occupational activities; Behavioral: REHACOP

• Registration Number: NCT02796417
• Lead Sponsor: University of Deusto

Brief Summary

This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Primary Completion: 2014-04
• Study Completion: 2014-04
• Study First Submitted: 2016-05-13
• Status Verified: 2016-06
• Study First Submitted QC: 2016-06-06
• Last Update Submitted: 2016-06-06
• Study First Posted: 2016-06-10
• Last Update Posted: 2016-06-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 111

Inclusion Criteria

• diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)

Exclusion Criteria

• evidence of alcohol or drug abuse in the last 30 days
• previous history of significant lack of consciousness
• mental retardation
• relevant neurological or medical condition

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	Occupational activities	Occupational activities
Rehacop group	REHACOP	Cognitive rehabilitation

Primary Outcome Measures

Name	Time	Method
change in processing speed after receiving cognitive remediation	4 months	Processing speed was assessed with Digit Symbol subtest from Wechsler Adult Intelligence Scale-III (Wechsler 1997)
Change in global functioning after receiving cognitive remediation	4 months	global functioning measured with Global Assessment of Functioning (GAF)
change in verbal memory after receiving cognitive remediation	4 months	Verbal memory performance was assessed with the Hopkins Verbal Learning Test-HVLT (Brandt and Benedict 2001)
Change in functional competence after receiving cognitive remediation	4 months	functional competence was measured with San Diego UCSD Performance-Based Skills Assessment- UPSA

Secondary Outcome Measures

Name	Time	Method
change in clinical symptoms after receiving cognitive remediation	4 months	Clinical symptoms was measured with Positive and Negative Syndrome Scale (PANSS)
change in emotion perception after receiving cognitive remediation	4 months	emotion perception was assessed with Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT)
change in theory of mind after receiving cognitive remediation	4 months	Theory of mind was assessed with Happe Strange Stories Test
change in social perception after receiving cognitive remediation	4 months	Social perception was assessed with the Social Featuring Recognition Test (SFRT)

Trial Locations

Locations (1)

University of Deusto; 🇪🇸 Bilbao, Biskai, Spain