The outcome of Botox injection in the internal anal sphincter with and without ultrasound guided in children with constipatio
Phase 3
- Conditions
- Constipation.ConstipationK59.0
- Registration Number
- IRCT20230704058661N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Children over 3 years old with constipation
Failure to respond to medical treatment and lifestyle changes by gastroenterologists
The typical Hirschsprung appearance is not seen in the barium enema
Presence of tuberculous ganglion in rectal biopsy
No contraindications for botox injection
Consent to participate in the study
Exclusion Criteria
Constipation caused by Hirschbrung
Taking aminoglycoside drugs, penicillamine, quinine, and calcium channel blockers
Having neuromuscular junction diseases such as myasthenia gravis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of constipation. Timepoint: Two weeks, one and three months after botox injection. Method of measurement: Biography of the child's parents.;Fecal incontinence. Timepoint: Two weeks, one and three months after botox injection. Method of measurement: Observation.
- Secondary Outcome Measures
Name Time Method