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Skin Sterility After Ethyl-Chloride Spray

Completed
Conditions
Skin Sterility After Use of Ethyl-chloride Spray.
Registration Number
NCT01292850
Lead Sponsor
University of Medicine and Dentistry of New Jersey
Brief Summary

The aim of this study is to investigate sterility of ethyl-chloride topical anesthetic spray when used prior to an injection. The hypothesis is that the spray does not change the sterility of the injection site after skin is prepped.

Detailed Description

This is an IRB-approved, prospective, blinded, controlled study. In the first set of experiments, skin sterility is assessed. Healthy adult subjects are prepared for mock injections of shoulders and knees. No injection is performed. Each site has a set of 3 skin cultures: 1) prior to the alcohol prep (pre-prep), 2) post-alcohol prep (pre-spray), and 3) after ethyl-chloride was sprayed on the site (post-spray). In the second set of experiments, sterility of ethyl chloride is tested directly by culturing the liquid from the spray bottles.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15
Inclusion Criteria
  • age -- 18-85
  • healthy skin at shoulder and knee area
Exclusion Criteria
  • allergy to ethyl-chloride
  • skin lesions at shoulder or knee

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
culture positivity5 days

Cultures before and after Ethyl-Chloride spray are compared to see if there is any difference.

Secondary Outcome Measures
NameTimeMethod
Native skin flora5days

Cultures of skin prior to skin prep are taken to define to native flora at the shoulder and knee area.

Trial Locations

Locations (1)

UMDNJ UH

🇺🇸

Newark, New Jersey, United States

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