ACTRN12619001441101尚未招募未知
Discontinuing nucleos(t)ide analogue therapy for chronic hepatitis B -Is it safe and will it increase the rate of HBsAg seroconversion? A randomised pilot study
Dr Tien Huey Lim0 个研究点目标入组 40 人开始时间: 2019年10月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 60 Years（—）
- 性别
- All
入选标准
- •Non-cirrhotic patients with chronic hepatitis B (CHB), on nucleos(t)ide analogue (NA) therapy for at least 2 years
- •- Age 18-60 years
- •- Normal ALT level at screening
- •- HBV DNA undetectable levels x3 (>6 months apart)
- •- HBsAg levels <100 IU/mL within the last 3 months
排除标准
- •- Patients with cirrhosis/severe fibrosis (Fibroscan >9kpa), hepatocellular carcinoma
- •- Other significant medical co-morbidities
- •- Patients who have history of significant non compliance
- •- Significant alcohol consumption (>30g/day for women and >50g/day for men)
- •- Poor venous access
研究者
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