Comparison the effects of Acetaminophen and Ibuprofen on emotions

Phase 2

Recruiting

• Conditions: Healthy volunteers.; Other symptoms and signs involving emotional state; R45.89

• Registration Number: IRCT20190729044367N1
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

All participants should be right-handed
They have normal hearing sensitivity
No reported history of brain diseases like depression or alzheimer.
No head trauma, stroke or injury
Do not have history of alcohol and smoking (especially a few days before the signal is recorded)

Exclusion Criteria

Pregnancy
Breastfeeding
Preexisting neurological or psychological disorders
Severe liver failure based on Child-Pugh Score
Renal failure (Glomerular Filtration Rate (GFR) < 15 mL/min)
History of prior anti-psychotic or anti-epileptic use
Allergy to oral Acetaminophen and non-steroidal anti-inflammatory drug (NSAID)
History of smoking or alcohol abuse

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Emotional arousal score in questionnaire between 0-5. Timepoint: Survey the emotional state immediately after the recording for checking the effect of painkiller. Method of measurement: Asking participants after recording and score the music from 0-5. and observe and analyze brain signals in both happiness and sadness.