A Randomized Controlled Trial Comparing 7 day Vonoprazan based Triple Therapy and 14 day Omeprazole based Triple Therapy for Helicobacter pylori Infectio

Phase 4

Recruiting

• Conditions: H. Pylori infection; Helicobacter pylori treatment, vonoprazan based triple therapy, omeprazole based triple therapy

• Registration Number: TCTR20210130003
• Lead Sponsor: Medical research, Rajavithi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-30
• Study Completion: 2021-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Present of H. Pylori: confirm by one or more of the following methods
- Urea breath test
- Rapid urease test or
- Histology
2. Patient agree to joint the project

Exclusion Criteria

1. History of allergy to PPI, vonoprazan, penicillin, clarithromycin
2. Previous H. Pylori eradication therapy
3. History of antibiotic to effect h. Pylori treatment before 1 month
4. History of GI malignancy or surgery
5. Serious cardiovascular, pulmonary, renal, hepatic disorder or malignancy
6. Pregnancy or lactating
7. History of drug or alcohol abuse

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Eradication rates of H. Pylori infection 6 week Chi-square

Secondary Outcome Measures

Name	Time	Method
Adverse event of H. Pylori treatment 3 and 14 day Chi-square