A clinical trial to study the effect of two regimen, opioid and opioid free anaesthesia regimen in patients undergoing laparoscopic surgeries.
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/12/060681
- Lead Sponsor
- DrAshu Sara Mathai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American society of anaesthesiologist (ASA) classification I,II,III
Patients undergoing elective, laparoscopic, non cardiac surgeries of less than 4 hours
duration
Exclusion Criteria
Patients who refuse consent/lack the capacity to give consent
Patient with known allergy to the study drugs used
Patient with co-existing liver or renal disease
Patients undergoing conversion to open surgical technique
Patients with preoperative uncontrolled hypertension (Preoperative BP >190/110 mmhg) or
hypotension (MAP <65 mmhg)
Pregnancy
Patients with Seizure disorder
Patients with psychiatric illnesses or on antipsychotic medications
Patients with Cardiac arrhythmias /AV block/ Bradycardia ( <50/min)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraoperative haemodynamic stability (heart rate,blood pressure) <br/ ><br>post operative analgesia using Numerical Rating ScoreTimepoint: Intraoperative haemodynamic stability (heart rate,blood pressure) <br/ ><br>at 0,3,6,12,24 hours
- Secondary Outcome Measures
Name Time Method gastrointestinal recovery after surgery,haemodynamic instability,postoperative nausea and vomiting, respiratory depression,pruritusTimepoint: 24hours;quality of Recovery-15Timepoint: 24 hours;Ramsay sedation scoreTimepoint: 24hours