Prevalence of bleeding disorders in women with menorrhagia

Completed

• Conditions: heavy menstrual bleeding; menorrhagia; 10064477; 10083624

• Registration Number: NL-OMON39998
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 287

Inclusion Criteria

- Healthy controls with regular normal menstrual bleeding
Age *18 years
Written informed consent
- Patients with regular heavy menstrual bleeding (<=menorrhagia)
Age *18 years
Written informed consent

Exclusion Criteria

- Healthy controls with:
1. postmenopausal, postcoital or intermenstrual bleeding.
2. an intra-uterine device or hormonal treatment.
3. anticoagulant, antithrombotic therapy or use of non-steroidal anti-inflammatory drugs (NSAIDs).
- Patients with:
1. postmenopausal, postcoital or intermenstrual bleeding.
2. an intra-uterine device or hormonal treatment.
3. anticoagulant, antithrombotic therapy or use of non-steroidal anti-inflammatory drugs (NSAIDs).

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Plasma FXI levels.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>FXI gene mutations/polymorfisms.<br /><br>Prevalence of bleeding disorders in patients with menorrhagia. </p><br>