Ganglion cell-inner plexiform layer thickness measured by Cirrus high-definition optical coherence tomography enhances glaucoma diagnosis in patients with moderate or high myopia

Completed

• Conditions: Glaucoma in moderate and high myopic patients.; Glaucoma; Myopia; High myopia; Moderate myopia; Diagnostic procedures; Ganglion Cell-Inner Plexiform Layer Thickness; Spectral domain optical coherence tomography

• Registration Number: TCTR20210726001
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-12-22
• Study Start: 2021-07-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Best-corrected visual acuity (BCVA) 20/40 or better
2. Spherical equivalent less than or equal -3.0 diopters

Exclusion Criteria

1. Subjects with retinal or macular pathology
2. Visual associated systemic or neurologic diseases
3. Received drugs with known side effects to macula eg. chloroquine ethambutol
4. Previous intraocular surgery or laser within 1 month
5. Inability to cooperated with the examination
6. Have allergic reaction to the eye drops used in the protocol

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ganglion cell-inner plexiform layer thickness After end of the intervention Cirrus spectral domain optical coherence tomography

Secondary Outcome Measures

Name	Time	Method
Diagnostic abilities to detect glaucoma with optical coherence tomography in moderate and high myopic patients After end of the intervention Area under the receiver operating characteristic curve