Patient-controlled remifentanil analgesia (PCA) during oocyte retrieval for IVF/ICSI procedures

Phase 4

Completed

• Conditions: 10013356; fertility procedure; In vitro fertilization

• Registration Number: NL-OMON34877
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 78

Inclusion Criteria

- Female subjects who undergo elective IVF/ICSI
- Age 18-45 years
- Informed consent

Exclusion Criteria

- Not willing to receive analgesia
- Allergy for remifentanil or pethidine

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The major endpoint of our trail is a reduction in pain levels as measured by a<br /><br>10-point VAS during oocyte retrieval through transvaginal puncture. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoint of our trial will be: (if applicable)<br /><br>-difference between patient with or without endometriosis,<br /><br>-difference in puncture pain between left- or right ovary,<br /><br>-pain scores in the first three days post-puncture,<br /><br>-factors on influence on puncture pain,<br /><br>-level of sedation,<br /><br>-level of nausea during analgesia,<br /><br>-use of post-puncture medication,<br /><br>-IVF-related success parameters,<br /><br>-treatment costs,<br /><br>-patients* satisfaction with the analgesic method.<br /><br><br /><br>Other study parameters: (if applicable)<br /><br>-Patients* demographics</p><br>