Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy

Completed

• Conditions: Intraoperative Parathyroid Scores System
• Interventions: Procedure: Different range of thyroid surgery

• Registration Number: NCT03172312
• Lead Sponsor: Fujian Medical University

Brief Summary

Ready to establish the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy and study the clinical value of Intraoperative Parathyroid Scores System for thyroidectomy.

Detailed Description

IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.

Study Timeline

• Study Start: 2014-01-01
• Primary Completion: 2016-12-31
• Study Completion: 2016-12-31
• Status Verified: 2017-05
• Study First Submitted: 2017-05-29
• Study First Submitted QC: 2017-05-31
• Last Update Submitted: 2017-05-31
• Study First Posted: 2017-06-01
• Last Update Posted: 2017-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

1. postoperative pathology confirmed as thyroid papillary carcinoma;
2. for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy;
3. preoperative serum calcium, parathyroid hormone levels were normal;
4. intraoperative and postoperative clinical data integrity, standardized follow-up patients;
5. parathyroid is a tumor violation.

Exclusion Criteria

1. serious underlying disease;
2. age greater than 60 years of age or combined with arteriosclerotic disease;
3. patients with postoperative loss;
4. patients with parathyroid disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hemithyroidectomy	Different range of thyroid surgery	Patients need to do Hemithyroidectomy According to guidelines
Total thyroidectomy	Different range of thyroid surgery	Patients need to do total thyroidectomy According to guidelines

Primary Outcome Measures

Name	Time	Method
transplantation Parathyroid Scores correlated with transplanted parathyroid function	2014-2016	relation with transplantation Parathyroid Scores and transplanted parathyroid hormone
the value of IPSS and in situ Parathyroid Scores	2014-2016	relation with Intraoperative Parathyroid Scores and in situ Parathyroid Scores
predicted function of IPSS	2014-2016	IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested
value of IPSS in low PTH patients	2014-2016	IPSS and in suit PSS be recoded and D1，D14 PTH Ca2+ were tested

Secondary Outcome Measures

Name	Time	Method
value of IPSS for Surgeon and patient	2014-2016	description the clinic value

Trial Locations

Locations (1)

Wen-xin ZHAO; 🇨🇳 Fuzhou, Fujian, China