Respiratory Mechanics and Pleural Effusion
Completed
- Conditions
- Critically IllAcute Lung InjuryARDS
- Registration Number
- NCT00258518
- Lead Sponsor
- Policlinico Hospital
- Brief Summary
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.
- Detailed Description
In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will be able to estimate any possible role of pleural effusion on the respiratory mechanics.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- ALI/ARDS patients underwent invasive mechanical ventilation
Exclusion Criteria
- Haemodynamic instability
- Chronic obstructive pulmonary disease (COPD) patients
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Role of pleural effusion and respiratory mechanics 1 hour
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link pleural effusion to altered respiratory mechanics in ALI/ARDS patients?
How does pleural effusion affect lung elastance and chest wall compliance in acute respiratory failure?
Are there specific biomarkers that predict the development of pleural effusion in ARDS patients?
What are the adverse events associated with CT scan evaluation of pleural effusion in critically ill patients?
How do respiratory mechanics measured at the bedside compare to those in CT scan-guided assessments for ALI/ARDS?
Trial Locations
- Locations (1)
Policlinico Hospital
🇮🇹Milano, Italy
Policlinico Hospital🇮🇹Milano, Italy