Pregabalin effect on opioid withdrawal symptoms
Phase 3
- Conditions
- opiod withdrawal symptoms.
- Registration Number
- IRCT201702012266N6
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
being drug dependent based on DSM-V criteria; regular oral/smoking daily consumption of opium; using no other medication including psychiatric drugs and also other substances except cigarette; not using pain medications; absence of other comorbid psychiatric disorders; not having any special diseases in which addiction treatment is prohibited; no contraindication for pregabalin consumption; no use of any other medication interacting with pregabalin.
Exclusion criteria: lack of patients' interest for participation in the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Opioid withdrawal symptoms including; feeling sick; stomach cramps; muscle spasms or twitching; feeling cold; heart pounding; muscular tension;aches and pains;yawning;runny/watery eyes; difficulty sleeping. Timepoint: At the begining of the intervention initiation, at the end of 1st week, at the end of 2nd week and at the end of 3rd and 4th weeks. Method of measurement: based on SHOWS questionnaire.
- Secondary Outcome Measures
Name Time Method Side effects including; Vertigo; Drowsiness; Fatigue; Weight Gain; Tremor; Constipation; Mouth dryness. Timepoint: end of 1st week, end of 2nd week, end of 3rd week and end of 4th week. Method of measurement: questionnaire.