Carotid Atherosclerosis in Predicting Coronary Artery Disease

Recruiting

• Conditions: Coronary Atheroscleroses; Carotid Atherosclerosis
• Interventions: Other: coronary agiongraphy

• Registration Number: NCT06253962
• Lead Sponsor: Shanghai Zhongshan Hospital

Brief Summary

Carotid plaque burden and composition features, particularly lipid necrotic core, are significantly associated with severity of CAD stenosis. This study aims to explore the relationship between various phenotypic patterns of carotid atherosclerosis with the prevalence, phenotype, and severity of coronary atherosclerosis. The patients with chest tightness or chest pain will receive carotid artery ultrasonography before coronary angiography so as to explore the relationship between them.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-02
• Study First Submitted: 2024-02-04
• Study First Submitted QC: 2024-02-04
• Last Update Submitted: 2024-02-04
• Study Start: 2024-02-10
• Study First Posted: 2024-02-12
• Last Update Posted: 2024-02-12
• Primary Completion: 2026-12-31
• Study Completion: 2028-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• patients receive carotid ultrasound and coronary angiography

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
without carotid atherosclerosis	coronary agiongraphy	-
carotid atherosclerosis	coronary agiongraphy	-

Primary Outcome Measures

Name	Time	Method
MACE	two years after angiography	acute myocardial infarction; heart failure; cardiac death; revascularization

Trial Locations

Locations (1)

180 Fenglin Road; 🇨🇳 Shanghai, China