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Inflammation, oxidative stress and wound healing after ablation of atrial fibrillatio

Not Applicable
Completed
Conditions
Atrial fibrillation
Circulatory System
Registration Number
ISRCTN89619994
Lead Sponsor
Medical University of Vienna (Austria)
Brief Summary

1. 2011 results in: https://www.ncbi.nlm.nih.gov/pubmed/20692054 (added 31/05/2019) 2. 2012 results in: https://www.ncbi.nlm.nih.gov/pubmed/22102100 (added 31/05/2019)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Genders eligible for study: both
2. Age older than 18 years
3. Symptomatic, drug-resistant paroxysmal atrial fibrillation (self-terminating episodes lasting less than 7 days)
4. Patients referred to our department for catheter ablation of atrial fibrillation
5. Adequate anticoagulation for at least 1 month prior to admission (oral anticoagulation (target International Normalised Ratio [INR] 2 to 3) or treatment with weight-adjusted low-molecular-weight heparin

Exclusion Criteria

1. Pregnancy
2. Ongoing infections
3. Intracardiac thrombosis detected by trans-oesophageal echocardiography
4. Contraindications to anticoagulation
5. History of myocardial infarction or cardiac surgery within the last 3 months prior to admission
6. Pacemaker or other contraindications to Magnetic Resonance Imaging (MRI)
7. Denial or withdrawal of informed consent
8. Life expectancy less than 1 year

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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