Metabolic FingerPrinting

Recruiting

• Conditions: Genetic Disease
• Interventions: Other: No intervention

• Registration Number: NCT05305729
• Lead Sponsor: Arcensus GmbH

Brief Summary

The MetaPrint study aims to characterize the metabolic fingerprint of genetic diseases in order to enhance knowledge on the physiological disease status and establish so new tools for diagnosing, monitoring and personalizing treatment of genetic diseases.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-01
• Status Verified: 2022-03
• Study First Submitted: 2022-03-21
• Study First Submitted QC: 2022-03-30
• Last Update Submitted: 2022-03-30
• Study First Posted: 2022-03-31
• Last Update Posted: 2022-03-31
• Primary Completion: 2026-03
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• Informed consent is obtained from the participant or from the parent/ legal guardian
• The participant is 2 months or older
• The participant is diagnosed with a genetic disease
• The participant is a first degree relative of a subject diagnosed with a genetic disease

Exclusion Criteria

• Informed consent is not obtained from the participant or from the parent/ legal guardian
• The participant is younger than 2 months
• The participant is not diagnosed with a genetic disease
• The participant is not a first degree relative of a subject diagnosed with a genetic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Subjects with a genetic disease	No intervention	-

Primary Outcome Measures

Name	Time	Method
Number of newly identified, disease-specific Metabolic Fingerprints	5 years	Plasma-derived metabolite profiles that are specific for a particular genetic disease in comparison to healthy controls and other genetic diseases

Trial Locations

Locations (5)

University Hospital Center Mother Teresa; 🇦🇱 Tirana, Albania

Khyber institute of Child Health and Children Hospital (KICH); 🇵🇰 Peshawar, Pakistan

The Children's hospital & Institute of child health; 🇵🇰 Lahore, Punjab, Pakistan

Children's Hospital & The Institute of Child Health; 🇵🇰 Multan, Pakistan

Pakistan Institute of Medical Sciences (PIMS); 🇵🇰 Islamabad, Pakistan