Oxygenation and Pulmonary Function in Morbidly Obese Patients Undergoing Bariatric Surgery
Not Applicable
- Conditions
- Morbid Obesity
- Registration Number
- NCT01002599
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
This is a randomized controlled study in which morbidly obese patients undergoing bariatric surgery will be recruited in the preoperative clinic. Patients will be randomized into 2 groups to receive oxygen with Boussignac TM continuous positive airway pressure (CPAP) or conventional Venturi mask postoperatively immediately after extubation. The objective of the study is to examine if Boussignac TM CPAP results in improved oxygenation versus Venturi face mask when it is applied immediately after extubation in morbidly obese patients post bariatric surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
- Patient aged between 18 to 75 years of age
- American Society of Anesthesiologists' (ASA) class I to III
- Morbidly obese with a body mass index > 35 kg/m2
- Patients undergoing bariatric surgery
Exclusion Criteria
- Patient refusal
- Pre-existing cardiac failure, asthma, chronic obstructive pulmonary disease or interstitial pulmonary disease
- Systolic blood pressure less than 90 mmHg despite pharmacotherapy
- Hb < 70 g/L
- Impaired gastric emptying
- Severe psychiatric disorder
- Language barrier
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method PaO2/FiO2 ratio (PF ratio) immediately on arrival to postanesthesia care unit, 1 hour, 2 hours, and 24 hours post-extubation. 24 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Health Network
🇨🇦Toronto, Ontario, Canada
University Health Network🇨🇦Toronto, Ontario, CanadaDavid Wong, MDContact4166035118david.wong@uhn.on.ca