Evaluation of Repetitive Transcranial Magnetic Stimulation on the Cognitive Rehabilitation After Traumatic Diffuse Axonal Injury.

University of Sao Paulo1 site in 1 country30 target enrollmentJanuary 2014

ConditionsTraumatic Brain Injury Diffuse Axonal Injury

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Traumatic Brain Injury
Sponsor: University of Sao Paulo
Enrollment: 30
Locations: 1
Primary Endpoint: Evidence of improvement on Attentional processes measured by cognitive evaluation (Trail Making Test parts A and B; Stroop Test - Victoria Version; Symbol Digit Test)
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether repetitive Transcranial Magnetic Stimulation (rTMS) is effective in the cognitive rehabilitation of patients with diffuse axonal injury(DAI) after Traumatic Brain Injury(TBI).

Registry

clinicaltrials.gov

Start Date

January 2014

End Date

August 2017

Last Updated

8 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Sao Paulo

Responsible Party

Principal Investigator

Iuri Santana Neville Ribeiro

iurineville

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

•Clinical and radiological diagnosis of traumatic brain injury.
•Between one to two years after traumatic brain injuri
•Must be able to sign the Informed Consent Form

Exclusion Criteria

•Drug addiction
•Uncontrolled epilepsy
•Extensive Cranial vault defects

Outcomes

Primary Outcomes

Evidence of improvement on Attentional processes measured by cognitive evaluation (Trail Making Test parts A and B; Stroop Test - Victoria Version; Symbol Digit Test)

Time Frame: One week and three months after rTMS.

Secondary Outcomes

Changes in cortical excitability measured by single and paired-pulse TMS(one week and three months.)
Evidence of improvement on Executive Function processes measured by cognitive evaluation.(one week and 3 months.)
Evidence of improvement on Motor Coordination measured by cognitive evaluation.(one week and three months.)