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Clinical Trials/NCT01695213
NCT01695213
Completed
Phase 4

A Randomized Comparative Study to Evaluate the Performance and Confirm the Safety of the Diocom Hip Syhstem in Cementless Hip Arthroplasty

Maastricht University Medical Center0 sites50 target enrollmentApril 2003

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Patients With Osteoarthritis of the Hip Joint Elligable for a Uncemented Hipprosthesis
Sponsor
Maastricht University Medical Center
Enrollment
50
Primary Endpoint
short term bone remodeling
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Thr purpose of this study is to compare the clinical and radiological results, as well as the femur bone density measurements of two uncemented total hip prostheses during 5 years of follow up.

Detailed Description

It is of great importance for the function of uncemented total hip arthroplasty that the anchorage of the prosthesis in the bone of the femur is sufficient. This is of great importance in the prevention of stress shielding of the bone and to insure tranfer of forces from the prosthesis to the femur. The symax hip stem is developed to optimize stress tranfer to bone and insure mechanical stability. In this study the symax hip stem is compared to the HA_Omnifit hip stem (a frequently used and long term evaluated uncemented hip prosthesis) During the fist two years of follow up DEXA mesurments of bone mineral density are performed. Also patient satisfaction, patient fuction score and radiological evaluation measurements are done during 5 years of follow up. Our primary objective is: comparison of the short term bone remodelling surrounding the Symax hip stem to the short term remodeling surrounding the Stryker Omnifit HA hip stem measured by bone densitometry, clinical and radiographic evaluation.

Registry
clinicaltrials.gov
Start Date
April 2003
End Date
July 2009
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or non pregnant female patients \>18 years
  • Patient with degenerative or traumatic changes to hip requiring hip replacement
  • Patient with BMI\<35
  • Patient signed informed consent

Exclusion Criteria

  • chronic anti-inflammatory medication use\> 3 months
  • revision surgery to the affected femur
  • Cancer therapy including immunosuppression, chemotherapy and radiation
  • Pathological fractures, delayed ossification or non-union is likely to occur

Outcomes

Primary Outcomes

short term bone remodeling

Time Frame: 6 times within 2 years

Bone remodeling is determined by measuring the Bone mineral density during time

complications and reoperations

Time Frame: during 5 years

Reporting all complications and reoperations of the two different hip prostheses

Secondary Outcomes

  • clinical performance(9 times within 5 years)
  • Radiological evaluation(9 times within 5 years)

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