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Clinical Trials/NCT00345228
NCT00345228CompletedNot Applicable

Myopic Macular Haemorrhages

Singapore National Eye Centre1 site in 1 country30 target enrollmentStarted: June 2004Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
30
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

  1. To identify the underlying causes of macular haemorrhages in patients with high myopia
  2. In the eyes found to have macular haemorrhages secondary to choroidal neovascularisation, we hope to identify the risk factors for the development of choroidal neovascularisation in high myopia
  3. To study the functional outcome of these eyes as assessed by visual acuity
  4. To study the morphological outcome of these eyes by clinical assessment (and fundal photography) and fluorescein angiography

Detailed Description

Primary Aims

  • To identify the underlying aetiologies of macular haemorrhages in myopic eyes
  • To study the functional and morphological outcome of these eyes with macular haemorrhages 6 months later Secondary Aims
  • To study the subgroup of eyes with myopic choroidal neovascularisation (CNV), in particular the risk factors for CNV in myopes
  • To study the subgroup of eyes with macular haemorrhages in the absence of CNV

Plan of investigation:

  1. Patient with myopia (>-6.00DS) presents with loss of central vision
  2. Examination reveals a macular haemorrhage
  3. Investigations
  • Refraction
  • Axial length*
  • Fundus fluorescein angiography
  • Indocyanine green angiography*
  1. Determine if a myopic CNV is present or absent
  2. Management of patient: Treatment vs No treatment

Study Design

Study Type
Observational
Observational Model
Defined Population
Time Perspective
Other

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •High myopia (greater than -6.00DS)
  • •Macular haemorrhage

Exclusion Criteria

  • •Macular haemorrhages from other causes eg. diabetic retinopathy, hypertensive retinopathy
  • •Allergy to fluorescein or indocyanine green dyes

Investigators

Sponsor Class
Other Gov

Study Sites (1)

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