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临床试验/NCT01943448
NCT01943448Unknown不适用

Macular Hemorrhage in Myopic Eyes

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年8月最近更新:
适应症

试验速览

阶段
不适用
入组人数
30
试验地点
1
主要终点
visual acuity

研究概览

简要总结

Visual impairment in high myopic eyes is mainly due to the different types of myopic maculopathies, such as diffuse or patchy atrophy, lacquer cracks and choroidal neovascularization. Macular hemorrhage was one of those complications. Despite choroidal neovascularization, simple hemorrhage from rupture of Bruch's membrane and choroidal microcirculation is also the cause of hemorrhage. The prognosis of those eyes with simple hemorrhage is generally good. However, some patients had persistently poor vision after the absorption of the hemorrhage. In the literature, the visual prognosis in those patients was reported to be associated with the microstructure change under the optical coherent tomography (OCT) or the presentation of the autofluorescence. The investigators will collect the patients with high myopia and presenting with macular hemorrhage. High resolution OCT and autofluorescence imaging will be used to analyze the change of the microstructure of retina and its correlation with the visual prognosis.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Myopia more than -6D
  • Macular hemorrhage inside arcade
  • Patients who are willing to visit our clinic and receive examination regularly for at least 1 year

排除标准

  • Patients who cannot cooperate.
  • Macular hemorrhage unrelated to myopia

结局指标

主要结局

visual acuity

时间窗: 1 year

visual acuity during follow up and its correlation to other factors

次要结局

  • Optical coherence tomography(1 year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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