临床试验/NCT02054390

NCT02054390已完成不适用

Angiotensin Converting Enzyme Inhibitor Therapy and Periprocedural Myocardial Infarction in Patients With Metabolic Syndrome

Ankara University1 个研究点分布在 1 个国家目标入组 459 人开始时间: 2014年2月最近更新: 2014年6月20日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Ankara University
入组人数: 459
试验地点: 1
主要终点: Periprocedural myocardial injury (MI)

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Metabolic syndrome (MS) has been reported as a risk for cardiovascular events. The aim of the present cohort study is to investigate whether ACEi therapy reduces the rate of periprocedural myocardial injury (PPMI) after elective percutaneous coronary intervention (PCI) among patients with metabolic syndrome.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 80 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•metabolic syndrome
•elective percutaneous coronary intervention with angiographically successful stent implantation

排除标准

•acute coronary events
•renal failure
•needed the use of IV glycoprotein IIb/IIIa receptor inhibitors were excluded
•left main coronary artery disease
•chronic total occlusion
•high levels of baseline CKMB or troponin
•any contraindication of aspirin, clopidogrel or ACEi treatment

结局指标

主要结局

Periprocedural myocardial injury (MI)

时间窗: 24 hours after (percutaneous coroary intervention) PCI

Periprocedural MI was defined as cardiac Troponin I release \[5 times ULN\] 24 hours after percutaneous coronary intervention

次要结局

Periprocedural myonecrosis(24 hours after PCI)

研究者

发起方

Ankara University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Özgür Ulaş Özcan

Ankara University

研究点 (1)

Loading locations...

相似试验

已完成

1 期

Evaluation of 3-V Bioscience-2640 to Reduce de Novo Lipogenesis in Subjects With Characteristics of Metabolic SyndromeMetabolic Syndrome

NCT02948569University of Missouri-Columbia12

已完成

不适用

Prevalence of Metabolic Syndrome in Patients With Intermittent ClaudicationIntermittent ClaudicationMetabolic Syndrome X

NCT00946868University of Sao Paulo170

暂停

不适用

Acute cardiometabole risico’s tijdens de behandeling met haloperidol bij ouderen.ouderen, delier, antipsychoticaelderly, delirium, antipsychotics

NL-OMON21267Tergooiziekenhuizen128

已完成

不适用

Cardiovascular Risk Evaluation in Clinical Practice in Metabolic Syndrome PatientsMetabolic Syndrome

NCT00171548Novartis600

已完成

不适用

Effect of Physical Activity and Diet on the Treatment of Metabolic SyndromeMetabolic Syndrome

NCT00917917University Hospital, Clermont-Ferrand150