Comparison of Low and High Ligation in the Rectal Cancer
Not Applicable
Completed
- Conditions
- Rectal Cancer
- Interventions
- Procedure: resection of nerve fibers around IMAProcedure: preservation of nerve fibers around IMA
- Registration Number
- NCT00701012
- Lead Sponsor
- Wakayama Medical University
- Brief Summary
The purpose of this study is to evaluate the defecatory function when nerve fibers around the inferior mesenteric artery(IMA) and left colic artery(LCA) are preserved(so called low ligation ) or not(high ligation) in the rectosigmoid and rectal cancer surgery.
- Detailed Description
Fecal incontinence after anterior resection are often observed. Whether or not postoperative bowel function is influenced by the preservation of nerve fibers around the root of IMA and LCA (low ligation) is still unknown. So in this randomized controlled trial, we evaluate the efficacy of low ligation in terms of the bowel function.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- On the basis of whether anterior resection was anticipated at WMUH for rectosigmoid and rectal cancer, and appropriate informed consent was obtained.
Exclusion Criteria
- Patients who could not respond to medical interview for own bowel function
- Patients without an informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 resection of nerve fibers around IMA high ligation, which the IMA is ligated at its origin from the aorta 1 preservation of nerve fibers around IMA low ligation, which the IMA is ligated below the origin of the left colic artery
- Primary Outcome Measures
Name Time Method Assessment of bowel function 1 year
- Secondary Outcome Measures
Name Time Method comparison of leakage rate 2 weeks
Trial Locations
- Locations (1)
Wakayama Medical University, Second Department of Surgery
🇯🇵Kimiidera, Wakayama, Japan