CCRT with Prophylactic PALN regional RT for locally advanced cervical cancer (Cervix-IV)
Not Applicable
- Conditions
- Squamous cell carcinoma of the uterine cervix, Stage IIB (>4 cm in diameter) and IIIB disease
- Registration Number
- JPRN-UMIN000028672
- Lead Sponsor
- Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
- Brief Summary
A total of 106 patients were enrolled. Of these, 9 had major protocol violations and 2 did not receive treatment because of worsened general condition. Thus, 95 patients were evaluable. The 2-year local control, progression-free survival, and overall survival rate for all patients were 96%, 78%, and 90%, respectively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 106
Inclusion Criteria
Not provided
Exclusion Criteria
1. Severe concomitant illness 2. History of other malignancies within the past 5 years except basal cell carcinoma or squamous cell carcinoma in-situ of the skin 3. Tumor with infiltration of lower 1/3 of the vagina 4. Patients who are pregnant or lactating
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2-year progression-free survival rate
- Secondary Outcome Measures
Name Time Method 2-year overall survival rate, acute and late toxicities.