Prospective observational study on preoperative algorithm treatment for Borderline Resectable Pancreatic Cancer with positive radiological arterial invasion - Prospective study on preoperative algorithm treatment for BRPC-A

Second Department of Surgery, Wakayama Medical University0 个研究点目标入组 50 人开始时间: 2020年6月16日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. Cases with a history of severe drug hypersensitivity or drug allergy 2. Cases with a history of malignant tumor (* If there is a recurrence-free period of 5 years or more, and endoscopically curatively resected intramucosal cancer, curatively resected cervical cancer, and basal cell carcinoma of the skin Or squamous cell carcinoma can be registered) 3. Cases with active infection 4. Patients with peripheral sensory neuropathy (Grade 2 or higher) 5. Cases with a history of interstitial pneumonia or pulmonary fibrosis 6. Patients with uncontrolled ascites or pleural effusion 7. Cases receiving atazanavir sulfate 8. Cases with uncontrolled diabetes 9. Uncontrollable congestive heart failure, angina, hypertension, arrhythmia 10. History of neurologically or psychologically significant disease, and cases with complications 11. Cases with diarrhea (including increased number of stools and watery stools) 12. Pregnant women, lactating women, and cases of possible pregnancy (will), or women and men who are not willing to contracept during the study period and for a certain period (180 days) after the last administration of the study drug 13. Patients with active hepatitis B 14. Regarding UGT1A1*6 and *28 gene polymorphisms, have either of them as homozygotes (UGT1A1*6/*6, UGT1A1*28/*28) or both as heterozygotes (UGT1A1*6/*28) Case

发起方

Second Department of Surgery, Wakayama Medical University